Morphometry of interstitial fibrosis

Desquamative interstitial pneumonia: relationship to interstitial fibrosis.

Patchefsky, A. S., Israel, H. L., Hoch, W. S., and Gordon, Gloria (1973). Thorax, 28, 680-693. Desquamative interstitial pneumonia: relationship to interstitial fibrosis. The clinical course and radiographic and pathological findings in 14 patients having the histological pattern of desquamative interstitial pneumonia (DIP) have been studied. Four deaths occurred from cardiorespiratory failure ...

Familial Interstitial Pulmonary Fibrosis.

In 1944 Hamman and Rich first described a disease that caused an acute diffuse interstitial fibrosis of the lungs, and which resulted in the death of four patients within six months of the onset of symptoms. Since then countless further cases have been reported in the literature, and our knowledge of the subject has advanced. It is recognized that the interstitial fibrotic process may be locali...

Interstitial pulmonary fibrosis.

The study of animal models of IPF has demonstrated that there is a stereotyped response of the respiratory airspace walls to a wide variety of injuries. Inflammatory and immune effector cells play a major and complex role in the fibrosing process. They may contribute to the injury of the lung beyond the original insult. These cells secrete substances that play an important role in determining c...

Mathematical model of renal interstitial fibrosis.

Lupus nephritis (LN) is an autoimmune disease that occurs when autoantibodies complex with self-antigen and form immune complexes that accumulate in the glomeruli. These immune complexes initiate an inflammatory response resulting in glomerular injury. LN often concomitantly affects the tubulointerstitial compartment of the kidney, leading first to interstitial inflammation and subsequently to ...

Familial Incidence of Diffuse Interstitial Pulmonary Fibrosis.